Antoaneta Sawyer, PhD
Recent USDA statistics show that since 1970, the average daily caloric intake in the U.S. has increased by nearly 25 percent. Researchers at the Cornell University examined 52 paintings of the well known 15th century painting created by Leonardo da Vinci the “ Last Supper” and digitally compared the size of food and plate for a period of time of 1000 years with the most modern one.
Their report, published in The International Journal of Obesity (April, 2010), showed that the plate, as well as the entrée size enlarged by about two-thirds over the millennium while bread size increased by nearly 25 percent. (Wansink, B & Wansink, C.S.)
The World Health Organization (WHO) estimations are that by 2015, there will be more than 1.5 billion overweight consumers, with an incurring health cost beyond $117 billion per year in the US alone. (NH-WC "Beyond Holistic) Thus, the need of future research in the science of metabolomics for obesity control is strongly substantiated. (Source, Wiki, and PMV)
The new science of metabolomics is constantly discovering new mechanisms to control morbid obesity as part of the metabolic syndrome. Recently it was found a new connection between obesity as part of the metabolic syndrome disorder related to the use of probiotics and prebiotics, as regulators of the gut microflora (Source, Wiki)
Results from recent research suggested that there is a significant decrease in body mass index (BMI), linked to a modulation of gut peptides and appetite modulation that have been observed upon long term treatment of overweight and obese patients with probiotics and prebiotics. The study published in the Curr Opin Clin Nutr Metab Care (2005). also noted that the concept may be also applicable to humans, “Moreover, the metabolomic analysis will allow to select the potential new microbial targets related to obesity and related disorders in the future” (Delzenne & Cani, 2005).
Gut microorganisms, also termed “microbiota” are the trillions of bacteria that normally reside in the human GI tract, and affect nutrient absorption, energy and immunity regulation. Margaret Furtado MS, RD, LDN claims in her article"Probiotics, prebiotics, gut microbiota, and obesity" that ingestion of probiotics and their synbiotic use with prebiotics is highly recommended as preventative approach to the road of health and well-being (Source, BariatricTimes)
The rule that early gut microbiota composition can guide weight development throughout early childhood was established. Ingestion of probiotics is recommended as preventative approach to maintaining the balance of the intestinal microflora and thereby enhancing health and well-being (Furtado, 2009). The role of the gut microflora in affecting the caloric intake control and satiety is gradually being unraveled” are the statements of Prof. Glenn Gibson (University of Reading).
New science breakthrough study published in Nature (Ley, Turnbaugh, Klein & Gordon, 2006) reported that microbial gut flora is different between obese and lean people and that obese people are losing weight when probiotics are added. Two main divisions of beneficial bacteria—Bacteroides and Firmicutes—are recognized as normal residents in the gut, and the equilibrium between the two species is very important in determining an individual’s chance for obesity. This breakthrough is based on the finding that the obese people microflora reverted back to the one of the lean people, suggesting that obesity may have a microbial pathogenesis component.
Thus, the obesity phenomena is induced not so much by overeating, but as to the different metabolic activities of already modified gut flora facilitating the extraction of calories from ingested dietary substances that is storing calories in the adipose tissue for later use. It is obvious that there is an elevated rate of food ingestion in obese patients. Therefore, the attempt to modulate the equilibrium or gut microflora may have a role in the future prevention and treatment of obesity.
Probiotics are nonpathogenic live microorganisms that are believed to confer health benefits to the host when ingested (WHO). (Source, USProbiotics.com) As Gibson (2010) stated “The role of the gut microflora in affecting calorie control and satiety is gradually being unraveled.” The author’s conclusion is that prebiotics may beneficially modify bacterial populations in the guts and aid weight management, with “promising effects also shown in humans.” Larsen, Vogensen, Van den Berg & Anderson proved that "Gut microflora in human adults with type 2 diabetes differs from non-diabetic adults” (2010)
Prebiotics are non-digestible oligosaccharides believed to act as “fertilizers” of the colonic microflora, enhancing growth of beneficial residential organisms (e.g. Bifidobacterium, and Lactobacillus) (Reuter, 2001). Despite known as “non-digestible” the prebiotics are between the food fibers or ingredients that have a beneficial effect through their selective metabolism in the intestinal tract” (Gibson et al., 2004). Prebiotics are believed to offer health benefits on the host, explained with the activation or modulation of lipid metabolism most likely via the process of fermentation. (Source, NutritionNews)
The combination of prebiotics and probiotics, known as "synbiotic", is believed to show enhanced health benefits acting as a “functional food.” (Source, Invista.com) Recent studies reviewed the synergistic role of prebiotics and probiotics on obesity and suggested that individuals with obesity may have differing amounts of particular microflora (e.g. Firmicutes). (Source, Wiki) The combination of probiotics and prebiotics has been proposed to be used in food due to its health-enhancing, and anti-obesity properties to modify the gut flora to its beneficial ratio.
Photo credit: Flickr
The World Health Organization (WHO) estimations are that by 2015, there will be more than 1.5 billion overweight consumers, with an incurring health cost beyond $117 billion per year in the US alone. (NH-WC "Beyond Holistic) Thus, the need of future research in the science of metabolomics for obesity control is strongly substantiated. (Source, Wiki, and PMV)
The new science of metabolomics is constantly discovering new mechanisms to control morbid obesity as part of the metabolic syndrome. Recently it was found a new connection between obesity as part of the metabolic syndrome disorder related to the use of probiotics and prebiotics, as regulators of the gut microflora (Source, Wiki)
Results from recent research suggested that there is a significant decrease in body mass index (BMI), linked to a modulation of gut peptides and appetite modulation that have been observed upon long term treatment of overweight and obese patients with probiotics and prebiotics. The study published in the Curr Opin Clin Nutr Metab Care (2005). also noted that the concept may be also applicable to humans, “Moreover, the metabolomic analysis will allow to select the potential new microbial targets related to obesity and related disorders in the future” (Delzenne & Cani, 2005).
Gut microorganisms, also termed “microbiota” are the trillions of bacteria that normally reside in the human GI tract, and affect nutrient absorption, energy and immunity regulation. Margaret Furtado MS, RD, LDN claims in her article"Probiotics, prebiotics, gut microbiota, and obesity" that ingestion of probiotics and their synbiotic use with prebiotics is highly recommended as preventative approach to the road of health and well-being (Source, BariatricTimes)
The rule that early gut microbiota composition can guide weight development throughout early childhood was established. Ingestion of probiotics is recommended as preventative approach to maintaining the balance of the intestinal microflora and thereby enhancing health and well-being (Furtado, 2009). The role of the gut microflora in affecting the caloric intake control and satiety is gradually being unraveled” are the statements of Prof. Glenn Gibson (University of Reading).
New science breakthrough study published in Nature (Ley, Turnbaugh, Klein & Gordon, 2006) reported that microbial gut flora is different between obese and lean people and that obese people are losing weight when probiotics are added. Two main divisions of beneficial bacteria—Bacteroides and Firmicutes—are recognized as normal residents in the gut, and the equilibrium between the two species is very important in determining an individual’s chance for obesity. This breakthrough is based on the finding that the obese people microflora reverted back to the one of the lean people, suggesting that obesity may have a microbial pathogenesis component.
Thus, the obesity phenomena is induced not so much by overeating, but as to the different metabolic activities of already modified gut flora facilitating the extraction of calories from ingested dietary substances that is storing calories in the adipose tissue for later use. It is obvious that there is an elevated rate of food ingestion in obese patients. Therefore, the attempt to modulate the equilibrium or gut microflora may have a role in the future prevention and treatment of obesity.
Probiotics are nonpathogenic live microorganisms that are believed to confer health benefits to the host when ingested (WHO). (Source, USProbiotics.com) As Gibson (2010) stated “The role of the gut microflora in affecting calorie control and satiety is gradually being unraveled.” The author’s conclusion is that prebiotics may beneficially modify bacterial populations in the guts and aid weight management, with “promising effects also shown in humans.” Larsen, Vogensen, Van den Berg & Anderson proved that "Gut microflora in human adults with type 2 diabetes differs from non-diabetic adults” (2010)
Prebiotics are non-digestible oligosaccharides believed to act as “fertilizers” of the colonic microflora, enhancing growth of beneficial residential organisms (e.g. Bifidobacterium, and Lactobacillus) (Reuter, 2001). Despite known as “non-digestible” the prebiotics are between the food fibers or ingredients that have a beneficial effect through their selective metabolism in the intestinal tract” (Gibson et al., 2004). Prebiotics are believed to offer health benefits on the host, explained with the activation or modulation of lipid metabolism most likely via the process of fermentation. (Source, NutritionNews)
The combination of prebiotics and probiotics, known as "synbiotic", is believed to show enhanced health benefits acting as a “functional food.” (Source, Invista.com) Recent studies reviewed the synergistic role of prebiotics and probiotics on obesity and suggested that individuals with obesity may have differing amounts of particular microflora (e.g. Firmicutes). (Source, Wiki) The combination of probiotics and prebiotics has been proposed to be used in food due to its health-enhancing, and anti-obesity properties to modify the gut flora to its beneficial ratio.
Photo credit: Flickr
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